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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
21.52
Human Site:
Y617
Identified Species:
39.44
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
Y617
E
A
N
I
A
W
K
Y
Y
K
F
P
K
K
K
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
Y631
E
A
D
I
A
W
K
Y
Y
K
F
P
K
K
K
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
Y617
E
A
N
I
A
W
K
Y
Y
K
V
P
K
K
K
Dog
Lupus familis
XP_537704
2182
240593
Y626
E
A
N
I
A
W
K
Y
Y
K
V
P
K
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
Y617
E
A
N
V
A
W
K
Y
Y
K
V
P
K
K
K
Rat
Rattus norvegicus
NP_001100505
2040
223488
S522
F
G
Q
E
S
V
T
S
V
T
E
L
M
V
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
Y613
E
A
D
S
T
W
K
Y
Y
K
V
P
K
K
K
Chicken
Gallus gallus
XP_415884
2225
244861
D661
N
L
E
E
D
E
A
D
T
T
W
K
Y
Y
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
H563
S
S
S
P
L
H
Q
H
F
Y
P
P
S
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
T688
S
V
E
P
P
S
Y
T
D
H
A
A
G
G
G
Honey Bee
Apis mellifera
XP_393643
1982
216109
V464
D
C
L
P
V
P
S
V
G
S
P
G
S
P
A
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
G749
K
Y
N
R
W
K
P
G
M
S
R
A
E
K
I
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
93.3
93.3
93.3
N.A.
86.6
0
N.A.
73.3
6.6
N.A.
6.6
N.A.
0
0
13.3
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
13.3
N.A.
80
13.3
N.A.
46.6
N.A.
0
6.6
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
0
0
39
0
8
0
0
0
8
16
0
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
16
0
8
0
0
8
8
0
0
0
0
0
0
% D
% Glu:
47
0
16
16
0
8
0
0
0
0
8
0
8
0
8
% E
% Phe:
8
0
0
0
0
0
0
0
8
0
16
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
8
8
0
0
8
8
8
8
% G
% His:
0
0
0
0
0
8
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
31
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
8
0
0
0
0
8
47
0
0
47
0
8
47
54
54
% K
% Leu:
0
8
8
0
8
0
0
0
0
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% M
% Asn:
8
0
39
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
24
8
8
8
0
0
0
16
54
0
8
0
% P
% Gln:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
16
8
8
8
8
8
8
8
0
16
0
0
16
8
0
% S
% Thr:
0
0
0
0
8
0
8
8
8
16
0
0
0
0
0
% T
% Val:
0
8
0
8
8
8
0
8
8
0
31
0
0
8
0
% V
% Trp:
0
0
0
0
8
47
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
47
47
8
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _